Sucralfate, bismuth subcitrate, and gastric HCO3 in humans
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چکیده
منابع مشابه
Effect of bismuth subcitrate and sucralfate on rat duodenal and human gastric bicarbonate secretion in vivo.
Acid and alkali secretion have been examined together with prostaglandin E2 production in response to two mucosal protective drugs, colloidal bismuth subcitrate and sucralfate. Doses of colloidal bismuth subcitrate in the therapeutic range (120 and 1200 mg) had no effect on alkali secretion or luminal PGE2 output when perfused into the stomach of human volunteers. Similarly, in the anaesthetise...
متن کاملGastrocytoprotection by colloidal bismuth subcitrate (De-Nol) and sucralfate. Role of endogenous prostaglandins.
This study compares the gastroprotective effects of colloidal bismuth subcitrate (De-Nol) with those of sucralfate and a methylated analogue of prostaglandin E2 (PGE2) against acute gastric lesions induced by acidified aspirin and absolute ethanol in rats. Both De-Nol and sucralfate given orally prevented dose dependently the formation of gastric lesions by these ulcerogens, De-Nol being, respe...
متن کاملGastrocytoprotection by colloidal bismuth subcitrate ( De
This study compares the gastroprotective effects of colloidal bismuth subcitrate (DeNol) with those of sucralfate and a methylated analogue of prostaglandin E2 (PGE2) against acute gastric lesions induced by acidified aspirin and absolute ethanol in rats. Both De-Nol and sucralfate given orally prevented dose dependently the formation of gastric lesions by these ulcerogens, DeNol being, respect...
متن کاملReversible toxicity in poisoning with colloidal bismuth subcitrate.
We thank the staff of the Aylesbury Vale breast screening service for their help and Drs E Rose and M Orton for allowing us to study patients under their care. 1 Working Party on Breast Cancer Screening. Report to the health ministers of England, Wales, Scotland and Northern Ireland. London: HMSO, 1987. (Forrest report.) 2 Tabar L, Fagerberg CJG, Gad A, et al. Reduction in mortality from breast...
متن کاملAcid, pepsin, and mucus secretion in patients with gastric and duodenal ulcer before and after colloidal bismuth subcitrate (De-Nol).
Basal and pentagastrin stimulated gastric secretion was measured in seven patients with duodenal, and six with gastric ulcers before and after four weeks' treatment with colloidal bismuth subcitrate (as De-Nol), one tablet four times a day. Each duodenal and all but one of the gastric ulcers healed. After De-Nol there were no significant changes in basal, or pentagastrin stimulated volume, acid...
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ژورنال
عنوان ژورنال: Gut
سال: 1990
ISSN: 0017-5749
DOI: 10.1136/gut.31.8.958